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I heard that there are MQSeries performance issues when people try to implement a publish/subscribe communication model (one-to-many) using MQSeries queues. Also, from what I heard, MQSeries seems not to be well suited for handling high-volume real-time traffic such as in financial data feeds. In respect to MQSI performance issues, I'm not experienced enough with that product. I would suggest you contact an IBM representative for performance data related to MQSI.
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